Robert Jernigan Director of L. H. Baker Center for Bioinformatics & Biological Statistics Professor of Department of Biochemistry, Biophysics, & Molecular Biology 112 Office and Lab Building Iowa State University Ames, IA 50011 515-294-7278 fax:515-294-7278 email:jernigan@iastate.edu Curriculum Vita (pdf) ( short , long ) & Publications (pdf)

Research Interests

Computational studies on the structures of proteins, nucleic acids, and small molecules, and their interactions.

Overall the direction of our research has been to push towards the comprehension of the functions of extremely large structures and mechanism in general. We have pioneered approaches to coarse-grain molecular structures to facilitate the comprehension of large structural behaviors. Applications are often made to develop new molecular models and to investigate the molecular effectiveness of drugs.

• Protein Datamining
• Potential functions
• Protein Threading
• Protein Conformation Generation
• Secondary Structure Predictions
• Nucleic Acid Conformations
• Elastic models of Proteins
• Protein dynamics
• Molecular Models and Structure Predictions
• Molecular Mechanisms Enzymes
• Molecular Mechanisms Ribosome
• Cellular Mechanisms

 

Teaching

• BCB569 Structural Genome Informatics (with Zhijun Wu and Guang Song)
• BBMB541 Computational Biochemistry
• BCB593 Workshop in Bioinformatics and Computational Biology